Phage display technique identifies the interaction of severe acute respiratory syndrome coronavirus open reading frame 6 protein with nuclear pore complex interacting protein NPIPB3 in modulating Type I interferon antagonism.
Identifieur interne : 000D89 ( Main/Exploration ); précédent : 000D88; suivant : 000D90Phage display technique identifies the interaction of severe acute respiratory syndrome coronavirus open reading frame 6 protein with nuclear pore complex interacting protein NPIPB3 in modulating Type I interferon antagonism.
Auteurs : Su-Hua Huang [Taïwan] ; Tzu-Ying Lee [Taïwan] ; Ying-Ju Lin [Taïwan] ; Lei Wan [Taïwan] ; Chih-Ho Lai [Taïwan] ; Cheng-Wen Lin [Taïwan]Source :
- Journal of microbiology, immunology, and infection = Wei mian yu gan ran za zhi [ 1995-9133 ] ; 2017.
Descripteurs français
- KwdFr :
- Cellules cultivées, Humains, Immunoprécipitation, Interactions hôte-pathogène, Interféron de type I (antagonistes et inhibiteurs), Liaison aux protéines, Microscopie confocale, Phosphatidylinositol 3-kinases (métabolisme), Protéines virales (métabolisme), Techniques d'exposition à la surface cellulaire, Test ELISA, Virus du SRAS (physiologie).
- MESH :
- antagonistes et inhibiteurs : Interféron de type I.
- métabolisme : Phosphatidylinositol 3-kinases, Protéines virales.
- physiologie : Virus du SRAS.
- Cellules cultivées, Humains, Immunoprécipitation, Interactions hôte-pathogène, Liaison aux protéines, Microscopie confocale, Techniques d'exposition à la surface cellulaire, Test ELISA.
English descriptors
- KwdEn :
- Cell Surface Display Techniques, Cells, Cultured, Enzyme-Linked Immunosorbent Assay, Host-Pathogen Interactions, Humans, Immunoprecipitation, Interferon Type I (antagonists & inhibitors), Microscopy, Confocal, Phosphatidylinositol 3-Kinases (metabolism), Protein Binding, SARS Virus (physiology), Viral Proteins (metabolism).
- MESH :
- chemical , antagonists & inhibitors : Interferon Type I.
- metabolism : Phosphatidylinositol 3-Kinases, Viral Proteins.
- physiology : SARS Virus.
- Cell Surface Display Techniques, Cells, Cultured, Enzyme-Linked Immunosorbent Assay, Host-Pathogen Interactions, Humans, Immunoprecipitation, Microscopy, Confocal, Protein Binding.
Abstract
Severe acute respiratory syndrome coronavirus (SARS-CoV) proteins including ORF6 inhibit Type I interferon (IFN) signaling.
DOI: 10.1016/j.jmii.2015.07.002
PubMed: 26320399
Affiliations:
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Le document en format XML
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